The Skirmish at Matamoros on November 23, 1847, was a U.S. victory of Gen. Joseph Lane, over a detachment under Colonel Piedras guarding the depot of the Mexican Army Light Corps that had been harassing the U.S. Army line of communications on the National Road under Gen. Joaquín Rea late in the Mexican–American War.

A night march in the rain from Puebla brought General Lane's force to the outskirts of Izucar de Matamoros, early in the morning.

The surprised guards fled into the town with the Texan riflemen and Louisiana Dragoons in hot pursuit.

[1] Lane returned to Puebla the next day but was intercepted on the way, by a larger force under Gen. Rea in the Pass of Galaxara.

[1] The raid had destroyed the material needed to support an effective offensive by the Light Corps, rendering it a minor nuisance for the rest of the war.