The show is hosted by radio imaging Malcolm Ryker, American music journalist Allison Hagendorf, and produced by Chris Cantore.

The weekly show mixes rock and hip-hop music for affiliates across the U.S., Canada, and Mexico.

Rock-oriented Ryker had contacted hip-hop DJ Mike Czech, then at San Diego pop station XHITZ-FM (90.3 FM, "Z90"), with the idea of combining their respective formats in a blended mashup show.

[1][2][3][4][5] Today the show serves nearly 60 affiliates, including stations in Washington, D.C. (WWDC (FM)), Detroit, Atlanta's 105.7 Saturday nights and Tampa.

In recent years, Skratch 'N Sniff has also offered limited content to non-market affiliates from the show's annual Halloween special.