Dejanović was born on 4 July 1951 in Rača near Kragujevac, where she finished her elementary and secondary school.

She also served as the Director of Clinical-Hospital Center in Kragujevac from 1995 to 2001. when she was removed from management functions but she remained to work as a doctor.

She was the president of the Commission for Drugs and a member of the Governing Board of Medical research within Section of science and technology.

[7] In June 2023, she was proposed by the government of Serbia to become the minister of education after Branko Ružić's resignation.

[3] While speaking to the Crime and Corruption Reporting Network (KRIK) about her assets, she has said that "officials should be completely exposed to the public and the truth in detail.

[7] Her husband, Ranko Dejanović, took part in the controversial privatisation of Zastava Elektro that occurred in the 2000s and an indictment was brought against him in Kragujevac Court.