[3] Since the unanimous acceptance of the Union of Uzhhorod on the territory that includes present day eastern Slovakia in 1646, the history of the Slovak Greek Catholic Church was intertwined with that of the Ruthenian Greek Catholic Church for a period of several centuries.

After communists seized the country in April 1950, a "synod" was convoked at Prešov, at which five priests and a number of laymen signed a document declaring that the union with Rome was disbanded and asking to be received into the jurisdiction of the Moscow Patriarchate, later the Orthodox Church of Czechoslovakia.

During the Prague Spring in 1968, the former Greek Catholic parishes were allowed to restore communion with Rome.

For Greek Catholics in the Czech Republic, a separate Apostolic Vicariate was created, elevated in 1996 to an exarchate thus forming the Apostolic Exarchate in the Czech Republic (now considered part of Ruthenian Catholic Church); the 2007 Annuario Pontificio indicated that it had by then grown to having 177,704 faithful, 37 priests and 25 parishes.

In Slovakia itself, Pope John Paul II created an Apostolic Exarchate of Košice in 1997.