Ralph Sandford "Smack" Thompson (May 30, 1900 – October 31, 1981) was a college football player.

[1] Thompson was an All-Southern end for Kid Woodruff's Georgia Bulldogs of the University of Georgia, captain of its 1925 team.

On the eve of a 3–0 loss to Georgia Tech, he screamed out "Kill the SOB", referring to Doug Wycoff.

[5] "He was absolutely poison" wrote Morgan Blake about Thompson, "with reckless disregard for life and limb, he plunged into the thick of every play.

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