In molecular biology, Small nucleolar RNA RZ107/R87 refers to a group of related non-coding RNA (ncRNA) molecules which function in the biogenesis of other small nuclear RNAs (snRNAs).

These small nucleolar RNAs (snoRNAs) are modifying RNAs and usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis.

These two snoRNAs R87 and Z107 were identified in the plant Arabidopsis thaliana[1] and rice Oryza sativa[2] respectively.

Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.

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