Smithfield is a village in Fulton County, Illinois, United States.

According to the 2021 census gazetteer files, Smithfield has a total area of 0.47 square miles (1.22 km2), all land.

[4] Smithfield is served by the Keokuk Junction Railway, a subsidiary of Pioneer Railcorp.

Smithfield once had a grocery story, Bank, Hardware Store and Railroad Depot.

The old jail cells can be seen in the Red Brick School parking lot.

38.00% of all households were made up of individuals, and 24.00% had someone living alone who was 65 years of age or older.