The film notably features only female characters, played by Tabu, Jyothika, Sharbani Mukherjee and Ishitta Arun.

Best friends Vani "Vasu" Subramaniam (Josephine in Malayalam) and Radhika Menon are carefree pranksters at a prestigious ladies' college in Chennai.

At this point, Vasu and Radhika are introduced to Gayathri, a fiercely independent and strong police officer and an alumnus of their college.

However, this fantasy takes a whole new turn when an actual person named Ramesh calls and sends Radhika letters, claiming to be her boyfriend.

To end this nuisance, Vasu and Radhika invite Ramesh to their hostel during the college dance program and plan to trick him into blurt out the truth.

Realising that the noose is tightening and that the story of their innocence will not stand, Vasu and Radhika escape police custody and hide in an abandoned mansion on the outskirts of the city.

The young man who was pretending to be Ramesh, was actually a family friend, named Vikram, whom Malathi had been planning to marry Radhika off to.

The film concludes with Gayathri institutionalised at a mental asylum where the three girls, Vani, Radhika and Geetha, now close friends, pay her a visit.

However the producer reiterated that they have taken only the main thread from the Marathi story with the rest of the film, its sub-plots and the treatment are completely different from the original.

Seasoned actresses like Sukumari, Manorama, Lakshmi, KPAC Lalitha, Mita Vasisht, Tabu, and Dipti Bhatnagar also joined the all-female team.

Cinematographer Jeeva and art director Sabu Cyril also joined the team and they shot 90 per cent of the film in a college in Mysore and the rest in Chennai, also featuring live coverage of the Dasara (Dussera) festival of Mysuru.

[2] The film was subsequently made simultaneously in Tamil and Malayalam with a title of Raakilipattu, while a Hindi version was also planned in 2000.

[4] Jyothika prioritised her work in the project and thus delayed her schedules for Uyirile Kalanthathu in order to ensure the film was released as early as possible.

[13] Malini Mannath of Chennai Online wrote, "The first part moves with breezy fun" but concluded that "the script goes haywire in the second half, the shoddy treatment not helping matters either.