[6][7] Her father Venugopal Rao, was a Merchant Navy engineer and her mother Santha Kamakshi was a primary school teacher.

Describing herself as an "uncool geek" and stating she wished for validation, Dhulipala entered with the intentions of only clearing the first round to prove to her friends she could.

[19][20] In 2018, Dhulipala appeared in her first Telugu film Goodachari co-starring Adivi Sesh, playing a Psychology graduate.

[23] She also appeared in a pivotal role in Bard of Blood, an Indian fictional spy thriller Netflix series, based on the 2015 espionage novel of the same name as an intelligence agency operative.

[24] Dhulipala made her debut in Malayalam cinema with Geetu Mohandas directorial-feature Moothon alongside Nivin Pauly, in the same year.

[35] In 2024, Dhulipala expanded to American cinema, as an escort, in Dev Patel’s directorial debut Monkey Man, which he also starred in.

[10] In a mixed review, The Guardian's Adrian Horton described Dhulipala's presence as "alluring" but lamented the lack of characterisation she was given.