Her late father was Marcel Sisniega Campbell, a Mexican Grandmaster chess player and independent film director.

She also took acting lessons at Casa Azul and Centro Universitario de Teatro (CUT) in Mexico City.

[1] Sisniega began acting professionally at 15 and appeared in two films, Mujeres en el Acto[citation needed] and Arresto Domiciliario in 2006 and 2008 both by the acclaimed director, Gabriel Retes.

[3] In January 2013, Sisniega was officially confirmed as "Sofía López-Haro" in the Mexican teen drama series, Gossip Girl: Acapulco.

[6] In December 2013, Sisniega appeared in a print ad for PETA Latino's campaign, Real Beauty is Cruelty-Free.

[7] In 2014 Sofia played the lead, opposite to Brian Petsos, in the highly acclaimed Mischa Rozema’s science fiction short "Sundays" which had at least three studios vying for it during 2015.

[8] In January 2015, Sisniega was cast on the first Spanish-language Netflix original TV series, Club de Cuervos.

She also appeared in other ads that asked consumers to go vegan, use cruelty-free makeup, and personal care products.

Her paternal uncle, Ivar Sisniega, is a modern pentathlete and politician who competed in the Summer Olympic Games in the 1980s.

She speaks Spanish and English [2][12] In August 2014, she founded, "Milk Bar", a bakery featuring organic, vegan and gluten-free cookies and desserts, located in Mexico City.