In 2004, The Doctors Laboratory formed a partnership with the National Health Service's University College of London Hospital.

In 1995, Sonic Healthcare acquired the Adelaide practice Pathlab making it part of Clinpath Laboratories.

Sonic Clinical Trials began operating from the Douglass Hanly Moir Pathology site at North Ryde.

In 2001, Sonic Healthcare acquired Castlereagh Imaging (New South Wales), Castlereagh Imaging Hong Kong (HK), Hunter Imaging Group (New South Wales), Illawarra Radiology Group (New South Wales), Canterbury Medical Imaging (New Zealand), Palmerston North X-Ray (New Zealand), (through Sullivan Nicolaides Pathology) Consultant Pathologists in Townsville (Queensland) and Cairns Pathology Laboratory (Queensland), Queensland X-Ray Group, Illawarra Medical Laboratories (New South Wales), Clinipath Pathology (Western Australia), La Trobe Pathology (Victoria) and Bunbury Pathology (Western Australia) from Foundation Healthcare, and SKG Radiology (Western Australia's largest private diagnostic imaging practice).

Sonic Healthcare acquired Richard Haskell's NSW Central Coast Pathology practice in 2003, along with the Southside Diagnostic Services Group in Brisbane.

In the US, the company acquired CBLPath (Rye Brook, NY) and Physician's Automated Laboratory (Bakersfield, California).

[9] In 2011, Sonic acquired the Woestyn Laboratory (Belgium), cytopathology business Labor Dr. Steinberg (Germany), Central Coast Pathology (San Luis Obispo, California), and Allied Medical and Australian Skin Cancer medical centre groups.

In 2012, the company acquired Labor Oldenburg Dr. Müller (Germany) and the Western Australian pathology operations of Healthscope.

In Australia, the company acquired Adelaide Pathology Partners and the Medibank Workplace Health (WPH) and Travel Doctor businesses.

[10] In 2019, the company acquired Aurora Diagnostics (USA) and sold its interest in GLP systems (Germany).

In 2022, Sonic acquired a 19.99% state in Microba Life Sciences Limited - ASX:MAP (Queensland, Australia).

Sonic and Microba have agree on a strategic alliance to exclusively deliver Microba's microbiome testing Technology in Germany, the United Kingdom and Belgium as well as a non-exclusive distribution within Sonic's broader network including Australia, Switzerland, the United States and New Zealand.