She prevented looting and quartering in the city and county during the Thirty Years' War by skillfully negotiating with army commanders.

Sophia made a name for herself outside the county when she turned to Axel Oxenstierna in 1633 and demanded compensation for the damage his troops had done to her territory.

Sophia was a Calvinist, but this did not prevent her from benefitting from a cooperation with her brother-in-law John Louis of Nassau-Hadamar, who had reverted to Catholicism.

[3] Only two of her children reached adulthood: The English representative at the baptism of Henry Casimir in March 1612 at Arnhem was Sir Edward Cecil.

Cecil brought gifts of a cupboard of gilt plate, a diamond necklace with a locket, two horses, and an embroidered petticoat for Sophia Hedwig, who was a niece of Anne of Denmark.