She scored three goals at the 2024 Paris Olympics, where the United States women's national team (USWNT) won gold.

Born to parents Mollie and Kenny Smith, Sophia was raised in Windsor near Fort Collins, Colorado with her two older sisters Gabrielle and Savannah.

[6] Wilson attended Fossil Ridge High School in Fort Collins, where she played for the varsity soccer and basketball teams as a freshman.

[6] As a high schooler, Wilson and her family would frequently drive 3–4 hours from Fort Collins to Denver and back for soccer practice with youth national teams.

She was named to the Hermann Trophy watch list[3] and helped lead the Cardinal to win the 2019 NCAA College Cup.

[10] Wilson was named the College Cup's Most Outstanding Offensive Player and earned All-Tournament team honors.

[8] She made four appearances during the NWSL Fall Series and scored one goal in a 3–0 win against the Utah Royals FC.

[14] During her regular season league debut on May 16, 2021, Smith scored a brace against the Chicago Red Stars in a 5–0 win.

[20] Despite a knee injury that kept her out for three games after returning from the 2023 FIFA Women's World Cup, Wilson went on to finish the 2023 season as the league's top scorer.

[26][25][27] After being a part of the under-20 squad that finished runner-up at the 2018 CONCACAF U-20 Championship, Wilson was named to the USA U-20 roster for the 2018 FIFA U-20 Women's World Cup.

[38][39] The United States defeated Brazil 1–0 in the final on a goal from Mallory Swanson, securing the gold medal.

[citation needed] Wilson, along with USWNT stars Mallory Swanson and Trinity Rodman are known as "Triple Espresso.

"[45] They gave themselves the name during the 2024 Olympic tournament, where the trio scored 10 of the team's 12 goals en route to winning the gold medal.

[46] Wilson was featured on the June 2023 cover of Sports Illustrated along with national teammates Rose Lavelle, Alex Morgan, and Trinity Rodman.

[5] Wilson co-starred in a commercial for ESPN's SportsCenter starting in January 2023 with Megan Rapinoe and Becky Sauerbrunn.

[53] Wilson has endorsement deals with Nike, Inc.,[54] BioSteel Sports Nutrition,[55] Ally Financial,[56] Chipotle,[57] Clif Bar,[58] Hyperice,[59] and Gatorade.