Sacko served as Prime Minister from 9 April 1991 to 9 June 1992 during the first and transitional presidency of Amadou Toumani Touré.
He also holds a bachelor's degree in Project Management Planning from National School of Administration (ENA) and a Master and Ph.D. in Economics Development (Honours) from the University of Pittsburgh.
He also attended training courses and seminars at the West German Foundation for International Development (DSE), Institute for Economic Development of the World Bank and the General Accounting Office of the United States Congress.
[2] He became the first Malian to resign from the government in 1987 following a gold trading case involving the First Lady of Mali.
Outside of the government, Sacko has acted as a senior economist at the United Nations Development Program (UNDP) and Executive Secretary of the African Capacity Building Foundation (ACBF).