[4] Sousa competed in the Copa do Brasil for the first time in 1995, when they were eliminated in the preliminary round by Flamengo.

[8] The club competed in the Copa do Brasil in 2010, when they were eliminated in the first round by Vasco.

[9] Sousa also competed in the 2024 Copa do Brasil, when they made a historical campaign: In the first round, verdão knocked out Cruzeiro with a 2-0 win, for the first time making it to the second round.

Then, Sousa beat Petrolina Social Clube 1-0 and went to the third round.

Sousa Esporte Clube play their home games at Estádio Governador Antônio Mariz, nicknamed Marizão.