It elects 5 Members of the European Parliament (MEPs) using proportional representation by means of the single transferable vote.

[5][6] At the 2019 European Parliament election, a reapportionment following Brexit and the loss of 73 MEPs from the United Kingdom gave two additional seats to Ireland.

[10] At the 2024 European Parliament election, the counties of Laois and Offaly were transferred to Midlands–North-West, while South remains a 5-seat constituency.

The main urban areas (by population size) are Cork, Limerick, Waterford, Bray, Kilkenny, Ennis, Carlow, Tralee, and Wexford.

Following a recheck of the votes for O'Sullivan and Ní Riada after the 18th count, a full recount was requested by the Sinn Féin candidate.