South Africa competed at the 2022 World Aquatics Championships in Budapest, Hungary from 18 June to 3 July.

[1] South Africa entered 4 artistic swimmers.

[3] South Africa entered 4 open water swimmers (2 male[4] and 2 female [5]) South Africa entered 9 swimmers.

[6] The following is South African roster in the Water polo at the 2022 World Aquatics Championships – Men's tournament.

The following is South African roster in the Water polo at the 2022 World Aquatics Championships – Women's tournament.