[3][4] Despite the short notice of the tour, Cricket South Africa confirmed that tests for COVID-19 had been done and the team was ready to travel.

[5] Prior to the tour, India's last international match was the final of the 2020 ICC Women's T20 World Cup on 8 March 2020.

[6] The South African team arrived in Lucknow on 26 February 2021, before undergoing six days of quarantine.

[11] South Africa won the first two WT20I matches,[12] recording their first series win against India in the format.

[13] India won the final match by nine wickets, with South Africa winning the series 2–1.