The Transnet Freight Rail Class 45-000 of 2015 is a South African diesel-electric locomotive.

The acquisition of the Class 45-000 forms part of the largest-ever locomotive supply contract in South African history and the single-biggest investment initiative by a South African corporation.

It consists of contracts for the construction of 1,064 locomotives by four global original equipment manufacturers:[1][2][3] All the Class 45-000 locomotives were delivered in red TFR livery.