[6] In January 2022, the ECB set Yorkshire the deadline of spring 2022 to meet certain conditions to regain their international status for the match,[7] with the suspension being lifted the following month.

[10] On 18 July 2022, England's Ben Stokes announced that he would retire from ODI cricket following the first match of the series,[11] citing the physical and mental demands of playing all three formats.

[12] South Africa won the opening ODI match by 62 runs, after they had made their highest team total in the format in England.

[24][25] The third day's play was started with tributes paid to the Queen,[26] including a minute's silence followed by the national anthems.

[37] Rassie van der Dussen was ruled out of South Africa's squad for the third Test due to a left index finger injury.

[44] Before the series, Craig Young was forced to withdraw from Ireland's squad with Graham Hume named as his replacement.