Men's Sports: basketball, baseball, cross country, golf, tennis, indoor and outdoor track and field, football (FCS Independent 2011–2012, full Sun Belt Conference play began in 2013) Women's Sports: basketball, softball, cross country, golf, tennis, indoor and outdoor track and field, volleyball, soccer Though not officially recognized by the administration, the students of The University of South Alabama maintain a multi-sport battle cry "South in your Mouth."

On September 5, 2009, the South Alabama Jaguars defeated Hargrave Military Academy 30–13 in their first ever game, and finished their first ever football season on November 12, 2009, with a shutout of an NCAA Division III team with a 35–0 victory over Huntingdon (Ala.) College.

On September 17, 2011, South Alabama suffered its first loss in the new program's history when it traveled to Carter-Finley Stadium in Raleigh, NC against the North Carolina State Wolfpack.

The baseball team is typically a powerhouse in the Sun Belt Conference, and has produced a number of successful Major League players, such as Juan Pierre, Adam Lind, Luis Gonzalez, Jon Lieber, Marlon Anderson and David Freese.

Stanky Field seats 4,500 spectators, and features the Jon Lieber Clubhouse and Luis Gonzalez Hitting Facility.

Kittrell led the Jaguar baseball program to more than 1,000 victories, 18 NCAA Tournament appearances, and numerous Sun Belt Conference championships.

South Alabama followed that with three more 20-win seasons in a row, and in 2008 received an at-large bid to the NCAA tournament, but lost to Butler University in the first round.

Since the Sun Belt expansion to 13 members in the 2006–2007 season, South Alabama is second only to Western Kentucky in conference winning percentage (65.3% to WKU's 76.4%).