The Queen's Highway, a two lane paved and illuminated road without traffic lights, runs approximately 60 km (40 mi) from the northernmost edge of South Andros which is the port of Drigg's Hill, to the dockside settlement of Mars Bay.

Almost the entire population of South Andros lives in housing abutting the Queen's Highway and a few short, paved roads trailing off it.

The only other significant road is that leading west, inland, along the north side of Deep Creek, to Black Point, where there are a handful of additional homes.

South Andros' widest point is about 30 km (20 mi) east to west, but only the eastern fringe is inhabited, as most of the island consists of salty marsh and tidal estuaries.

Government-provided electric, telephone and rubbish disposal services are available to all homes on the island, with a major power generation plant located mid-island in the settlement called The Bluff or Blufftown.