South Derbyshire is a constituency[n 1] represented in the House of Commons of the UK Parliament since 2024 by Samantha Niblett of the Labour Party.

1983–1997: The District of South Derbyshire, and the City of Derby wards of Boulton, Chellaston, and Mickleover.

[n 3] Further to the 2023 Periodic Review of Westminster constituencies, which came into effect for the 2024 general election, the composition of the constituency is as follows (as they existed on 1 December 2020): This comprises the whole of South Derbyshire District, excluding the wards of Hatton and Hilton, which were transferred to Derbyshire Dales.

This constituency consists of rural and semi-rural settlements, including Repton (with its famous public school), in which a majority of voters have, in local elections since World War II, been Tory-voting, plus more historically industrial, and manufacturing-focussed settlements such as Swadlincote where the electorate has been for the most part Labour-voting.

Workless claimants were in November 2012 significantly lower than the national average of 3.8%, at 2.2% of the population based on a statistical compilation by The Guardian, and very close to that of the Mid Derbyshire seat, at 1.9%.