South Greenfield is a village in Dade County, Missouri, United States.

[4] According to the United States Census Bureau, the village has a total area of 0.16 square miles (0.41 km2), all land.

There were 28.1% of families and 30.0% of the population living below the poverty line, including 38.2% of under eighteens and 35.7% of those over 64.

South Greenfield was originally called Watkins, and under the latter name was laid out in 1881 when the railroad was extended to that point.

[8] A post office called Watkins was established in 1881, and the name was changed to South Greenfield in 1891.

[9] The Dilday Mill was formerly listed on the National Register of Historic Places.