It is claimed that there were Roman remains just outside South Marston in a field belonging to Rowborough Farm, but these have long disappeared.

Ermin Way, a major Roman road linking Silchester and Gloucester, passed close to the village on the south-west side, separating it from Stratton St Margaret.

[5] The present church, built in stone rubble with ashlar quoins and dressings, has a 13th-century chancel and 15th-century nave and west tower.

[13] In 1985, Honda bought the site, which straddles the boundary with Stratton St Margaret parish, and turned it over to car manufacture.

[16] In that year the site was sold to Panattoni, an American industrial real estate developer, who intended to use it for a large-scale logistics operation.

[18] The replacement buildings, to be called Panattoni Park, were to be built in stages over the next five or six years and cover around 5.5 million square feet.

[19] The principal book storage facility for Oxford's Bodleian Libraries has been on South Marston Industrial Estate since 2010.

Alfred Williams, poet and steam-hammer operator at Swindon Railway Works, died in South Marston on 10 April 1930 aged 52.