Seven, later six, Members of the European Parliament using closed party-list proportional representation allocated using the D'Hondt method of distribution were elected.

The constituency was abolished when Britain left the European Union on 31 January 2020.

The constituency consisted of the South West England region of the United Kingdom, comprising the ceremonial counties of Bristol, Cornwall, Devon, Dorset, Gloucestershire, Somerset and Wiltshire.

Brackets indicate the order in which candidates were elected and number of votes per seat won in their respective columns.

The Cornish nationalist party Mebyon Kernow campaigned for a separate European Parliament constituency for Cornwall.