It encompasses Washington, D.C., and the states of Delaware, North Carolina, South Carolina, and Virginia, as well Maryland with the exception of Garrett County at its western end; it also includes York and Lancaster Counties in Pennsylvania.

The Southeastern District includes approximately 219 congregations and missions, subdivided into 19 circuits, as well as 64 preschools, 21 elementary schools, and three high schools.

District offices are located in Alexandria, Virginia.

Delegates from each congregation meet in convention every three years to elect the district president, vice presidents, circuit counselors, a board of directors, and other officers.

Dr. William Harmon was elected and installed as district president in 2022.