It was the first airline to provide ACMI (Aircraft, Crew, Maintenance, Insurance) service for the wide-body Boeing 777F.

Its wide range of services included long-term ACMI, on-demand commercial charters, and Department of Defense Civil Reserve Air Fleet.

Southern Air’s operations also supported some of the world’s largest combination carriers as well as government agencies and non-government organizations.

The airline was established on March 5, 1999, by James Neff, out of the assets of Southern Air Transport.

On September 7, 2007, Oak Hill Capital Partners acquired majority ownership of Southern Air and merged Cargo 360 into the airline.