Southern Defense Command (SDC) was established on 17 March 1941 as the command formation of the U.S. Army responsible for coordinating the defense of the Gulf of Mexico coastal region of the United States.

A second major responsibility of SDC was the training of soldiers prior to their deployment overseas.

SDC's operational region covered the states of New Mexico, Texas, Oklahoma, Arkansas, Louisiana, Mississippi, Alabama, Tennessee, and the western half of the Florida Panhandle.

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