The Southern District is one of the 35 districts of the Lutheran Church – Missouri Synod (LCMS), and encompasses the states of Louisiana, Mississippi and Alabama, as well as the western portion of the Florida Panhandle; the rest of Florida is part of the Florida–Georgia District.

The Southern District includes approximately 170 congregations and missions, subdivided into 15 circuits, as well as 14 preschools, 17 elementary schools, and 1 high school.

Baptized membership in Southern District congregations is approximately 29,391.

[2] District offices are located in Slidell, Louisiana.

[3] Concordia College Alabama in Selma, founded in 1922 as part of the mission program of the Synodical Conference, was a member of the LCMS Concordia University System and was located within the district until its closure in 2018.