Greater Houston and Beaumont–Port Arthur are occasionally tied to the region, both for physically being on the southern end of the state and for businesses that use "South Texas" in its name.

There is no defined northern boundary, although it is believed to be at the city of San Antonio and from an east to west line extending from the Rio Grande near Maverick County to the Gulf of Mexico, but turning southeast at or near Lavaca County, and continuing towards the Gulf of Mexico to separate it from East Texas and Southeast Texas.

The very southern tip of South Texas, called the Rio Grande Valley, has fertile soils and is known for its citrus production.

South Texas weather is affected by the Sierra Madre Oriental mountains to the west, the Gulf of Mexico to the east, and the Chihuahuan Desert to the west/northwest.

In addition, areas in Texas that are slightly inland from the Gulf of Mexico, such as San Antonio that border the semi-arid climate zone, generally see a peak of precipitation in the spring, and a deep, drought-like nadir in midsummer.

The region of South Texas includes the semi-arid ranch country and the wetter Rio Grande Valley.

The coastal areas are warm most of the year due to currents of the Gulf of Mexico, but can get cold in winter if a strong front comes in, occasionally causing snow at sea level.

These drought conditions led to a string of dangerous wildfires across the state, and the enforcement of burn bans in 250 of the 254 counties in Texas.

South Texas is well known for strong Hispanic, primarily Mexican American and Tejano (the Spanish term for "Texan") influences, due to its proximity to Mexico.

The disputed area was between the Nueces River south of San Antonio and Corpus Christi, the King Ranch, and the Rio Grande.

Their mission was to find, kill or capture John King Fisher, leader of a band of cattle rustlers and cut-throats who had been terrorizing the area.

Led by Leander McNelly, the Special Force was given the task to bring law and order to an area of South Texas that lay between Corpus Christi and the Mexican border.

The Houston Chamber of Commerce and the Southern Pacific Railroad invited Japanese farmers to Texas to help area farms in the production of rice.

[13] Laredo Eagle Pass Brownsville Los Indios Falcon Heights HidalgoMcAllen Pharr Progreso Rio Grande City Roma San Antonio Corpus Christi Laredo Rio Grande Valley Other The only major professional sports team in South Texas is the San Antonio Spurs in the NBA.