The Southern Theatre is currently owned and operated as a home for live concerts, plays and opera by CAPA (the Columbus Association for the Performing Arts).

As a result, a group of businessmen decided to develop a new hotel and theater with modern construction and safety features on the southern edge of downtown.

The building was called "The Great Southern Fireproof Hotel and Opera House", and was designed by the local architectural firm of Dauben, Krumm, and Riebel.

In the 1970s the theater briefly returned to first run fare as the Towne Cinema, showing black exploitation movies.

Throughout the 1970s the Southern also hosted a weekly live Country Music Jamboree, sponsored by local radio station WMNI.