[4] Currently, FishBase classifies northern and southern leatherside chub as distinct species within the genus Lepidomeda.

Similar to northern leatherside chub, this species selects for small cobble in both pool and riffle habitats with little to no flow for spawning.

[9] These fish are found in cooler temperature water with moderate currents in creeks, rivers, pools, or riffles where they can continuously feed.

[11] The southern leatherside chub is considered a species of greatest conservation need according to the Utah Division of Wildlife Resources.

[12] This species is threatened by habitat degradation caused by water abstraction for irrigation, channelization, damming, urbanization, and poor farming practices which lead to siltation.