[3] He grew up in a home full of music and with his parents' big record collection of blues and jazz; his father played bass in bands.

The Van Zandt-written "I Don't Want To Go Home" became Southside Johnny's signature song, an evocative mixture of horn-based melodic riffs and sentimental lyrics.

Other notable songs included "The Fever", "Talk to Me", "This Time It's For Real", "Love on the Wrong Side of Town", and a cover of Springsteen's "Hearts of Stone".

In 1981, Southside Johnny and the Asbury Jukes appeared on the Canadian sketch comedy television show SCTV, featured as a "wedding band".

[7] During the 1980s Southside Johnny's recording contracts continued to change almost by album, but he continued to release records: Trash It Up (1983), a Latin freestyle-influenced album written by Billy Rush and produced by Nile Rodgers; In the Heat (1984) an album trying to reach out to "Adult Contemporary" radio; and At Least We Got Shoes (1986) where guitarist and Jersey shore fixture Bobby Bandiera took over songwriting and guitar work from Billy Rush and led the Asbury Jukes back to their original sound.

[citation needed] Songwriting credits on At Least We Got Shoes also contain a song co-written by Bandiera and singer Patti Scialfa, who was known as a Jukes collaborator since the 1980 album Love is a Sacrifice and who became a member of Bruce Springsteen's E Street Band in 1984.

[9] In 1987, Southside Johnny and the Jukes were featured in the film Adventures in Babysitting performing at a college frat party.

[citation needed] Southside Johnny performed the theme song for the 1990s television sitcom Dave's World, a cover of Billy Joel's "You May Be Right."

A few members of the Asbury Jukes would end up being part of The Max Weinberg 7 on the Late Night with Conan O'Brien television show, while some others went on tour and into the recording studio with artists such as Jon Bon Jovi, Mink DeVille, Graham Parker, and Robert Cray.

In 2007, Southside Johnny appeared in an episode of The Sopranos TV show entitled "Chasing It", where he performed the song "Bossman" with Nancy Sinatra.

Together with a 20-piece big band they recorded a cover album of songs written by Tom Waits, arranged and conducted by Rosenberg.

Southside Johnny and the Asbury Jukes continue to be a fixture on the U.S. Northeast music scene including New York, New Jersey, Pennsylvania, Massachusetts and Maryland, as well as throughout the UK and Europe.

[citation needed] On July 2, 2011, Southside Johnny and the Jukes recorded a live performance of Stevie Van Zandt's Men Without Women album at the Stone Pony in New Jersey for release on CD.

[21] In 2017, Southside Johnny and the Asbury Jukes appeared as themselves in the "Sic Transit Imperium" episode of the Showtime TV series Billions, performing "I Don't Want to Go Home" and "Looking for a Good Time.