[3] The spacecraft is named in honor of Russian scientist Konstantin Tsiolkovsky, who is today considered one of the fathers of modern rocketry and astronautics.

[4] On 15 December 2022 at 12:45 UTC, a "visible stream of flakes" was observed emanating from the Soyuz spacecraft, concurrent with a loss of pressure in the external radiator cooling loop.

[7] Two working groups were formed to find the cause of the incident, analyze the technical condition of the ship and develop recommendations for further actions for ground specialists and the cosmonauts.

[13] Until the replacement MS-23 docked to ISS, NASA and Roscosmos considered sending the MS-22 crew home with SpaceX Crew-5 in case of emergency.

[14] The change allowed for increased crew protection by reducing the heat load inside the MS-22 spacecraft for cosmonauts Prokopyev and Petelin in the event of an emergency return to Earth.

[16] After the spacecraft docked, the seat liners for Sergey Prokopyev and Dmitry Petelin were moved from MS-22 to MS-23 on 2 March ahead of their return in the Soyuz.