On 24 March 2022, the European Space Agency announced that Danish astronaut Andreas Mogensen would serve as backup pilot.

Axiom provided the flight opportunity to MBRSC professional crew members through an agreement with the United Arab Emirates Space Agency.

[10] This ensures both countries have a presence on the station, and the ability to maintain their separate systems if either Soyuz or commercial crew vehicles are grounded for an extended period.

[11] The sixth SpaceX operational mission in the Commercial Crew Program (CCP) was launched on 2 March 2023 and lasted approximately six months.

[13] The first launch attempt was scrubbed at T−02:12 minutes due to an issue with the TEA-TEB spontaneous ignition fluid (times are UTC).