The Ambassador of Spain to the Holy See is the Kingdom of Spain's foremost diplomatic representative in the Holy See.

The ambassador is appointed to the Council of Ministers, they direct the work of all the offices that depend on the embassy, based in Vatican City.

Likewise, it informs the Spanish Government about the evolution of events in the Holy See, negotiates on behalf of Spain, can sign or ratify agreements, observes the development of bilateral relations in all fields and ensures the protection of Spanish interests and its citizens in the Holy See.

The current ambassador is María Isabel Celáa Diéguez, who was appointed by Pedro Sánchez's government on 26 January 2022.

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