Reina Sofía (F84) is the fourth of six Spanish-built Santa María-class frigates of the Spanish Navy.

The Harpoon missiles have a range of 50 nmi (93 km; 58 mi) at Mach 0.9 carrying a 227-kilogram (500 lb) warhead.

The vessels also mount a single OTO Melara 76-millimetre (3.0 in)/62 calibre naval gun capable of firing 85 rounds per minute up to 8.7 nmi (16.1 km; 10.0 mi) with each shell carrying a 6 kg (13 lb) warhead.

[1][a] For AAW defence, the ships mount a single Meroka 20 mm (0.79 in)/120 12-barrelled close-in weapons system (CIWS) capable of firing 3,600 rounds per minute up to 2 km (1.2 mi).

[4] As long-hulled versions of the Oliver Hazard Perry class, the Santa María-class frigates have twin hangars to accommodate up to two Sikorsky SH-60B Seahawk Light Airborne Multi-Purpose System (LAMPS) III helicopters though only one is usually embarked.

[10] In May 2023 Reina Sofía was deployed off the coast of East Africa in order to evacuate civilians after an escalation in violence in Sudan.

[11] The frigate evacuated 162 civilians of different nationalities from within the European Union from Sudan to Saudi Arabia.