"Speed of the Sound of Loneliness" is a song written by American singer-songwriter John Prine and recorded on his 1986 album German Afternoons.

[1] The song gained further fame with a duet recording by Prine and American singer Nanci Griffith on the latter's 1993 album Other Voices, Other Rooms[2] and the release of the track as a single.

Irish singer Susan McCann recorded a version in the early 90s along with a video and also included the track on her 2016 compilation album Through The Years.

Dave Matthews performed it live from his home studio as a tribute to Prine on The Late Show with Stephen Colbert on April 9, 2020.

The track also appears on Kurt Vile's extended play Speed, Sound, Lonely KV, released in October 2020.