The song features guest appearances from Bone Thugs-n-Harmony's Krayzie Bone and Twista and sampled The Walker Brothers' "My Ship Is Coming In" from their Take It Easy with the Walker Brothers album.

The single is a double A-side with "Hold Ya Head", a song which samples "Johnny Was" from Bob Marley's Rastaman Vibration album by his reggae band The Wailers and "Suicidal Thoughts" from Biggie's Ready to Die for his vocals.

's and Bone Thugs-n-Harmony's acclaimed collaboration on the song "Notorious Thugs".

In "Notorious Thugs", Biggie changed his normally smooth flow to a faster melodic pace to emulate Bone's trademark flow and "Spit Your Game" references this by including two fast verses by Twista and Krayzie Bone.

It is set in a recording studio as a "Battle for the Krown" is taking place.