Spitamen District (Russian: Спитаменский район; Tajik: Ноҳияи Спитамен) is a district in north-central Sughd, Tajikistan, stretching across the province's narrow part from the border with Uzbekistan to the border with Kyrgyzstan.

[1] Formerly called Nau District (Russian: Науский район) or Nov District (Tajik: Nohiya-i Nov, Ноҳияи Нов; Persian: ناحیۀ ناو), it was renamed Spitamen district by a resolution of parliament in November 2003.

[4] The district capital is Navkat, located south-west of Khujand.

The district is named after Spitamen who led the Sogdians in a revolt against the forces of Alexander the Great in 329-328 BCE.

[5] The district has an area of about 400 km2 (200 sq mi) and is divided administratively into one town and six jamoats.