Spofford is a city in Kinney County, Texas, United States.

[4] It is on the east side of Texas State Highway 131, which leads north 10 miles (16 km) to Brackettville, the county seat, and south 24 miles (39 km) to U.S. Route 277 in the Rio Grande valley.

According to the United States Census Bureau, Spofford has a total area of 0.2 square miles (0.6 km2), all land.

About 16.7% of all households were made up of individuals, and 16.7% had someone living alone who was 65 years of age or older.

At Spofford, they laid a spur to Eagle Pass, and the main line continued west to Langtry.

Amtrak’s Sunset Limited passes through the town on Union Pacific tracks, but makes no stop.