[5] Spotswood station opened on 1 December 1878[4] and, like the suburb itself, was named after John Stewart Spottiswoode, a local resident who purchased land in the area in 1841.

[4] In 1989, boom barriers replaced interlocked gates at the Hudson Road level crossing, located at the up end of the station.

It was decommissioned on 12 August 2001,[9] along with the removal of the crossover at the up end, a number of dwarf signals and a siding.

[5] In 2007, the remains of some sidings that ran along public roads in the area were removed by Hobsons Bay Council.

[5] On 26 October 2022, the Level Crossing Removal Project announced that the level crossing will be grade separated by 2030, with the railway line likely to be rebuilt over the road, and will include a rebuilt station.