Spree-Neiße (Lower Sorbian: Wokrejs Sprjewja-Nysa, pronounced [ˈwɔkrɛjs ˈsprʲɛwʲa ˈnɨsa] ; Polish: Powiat Sprewa-Nysa, Polish pronunciation: [/ˈpɔvjat ˈsprɛva ˈnɨsa/]) is a Kreis (district) in the southern part of Brandenburg, Germany.

The crayfish in the topleft symbolizes Cottbus-Land, and is also present in the coat of arms of the city of Cottbus.

The lion in the topright is the symbol of the Kingdom of Bohemia, as Spremberg was owned by the Bohemian kings.

The deer antler in the bottomright symbolizes Forst, and was taken from the coat of arms of the Lords of Biberstein.

The crown in the bottomleft represents the kings of Bohemia again, but this time symbolizing Guben.