Her lead roles in Indrajaalam (1990) as Mohanlal's heroine and Cheriya Lokavum Valiya Manushyarum (1990) are well noted.
Sreeja was born to theatre artists Sreedharan and Usha on 18 April 1971 in Thiruvananthapuram, Kerala.
She made her debut as a heroine with Annakutty Kodambakkam Vilikkunnu (1989), the first film directed by Jagathy Sreekumar.
She went on to act as a heroine to many actors, including Mohanlal in Indrajaalam (1990) and Mukesh in Cheriya Lokavum Valiya Manushyarum (1990) and Kazhchakkappuram (1992).
She is married to Sandhana Pandian who is from Tamil Nadu, co-star of her film Sevvanthi since 2 June 1993.