The aerodrome was built in the 1930s as a regional airport in the Haute-Normandie, probably using a circular grass airfield, with airplanes taking of in any direction into the prevailing wind at the time of takeoff.

Its initial use was by Jagdgeschwader 2 (JG 2), in late June 1940 which was being rotated though several different airfields in northwest France flying Messerschmitt Bf 109Es.

[1] From July 1942 onward, St-André was used primarily as a day interceptor fighter airfield against the USAAF Eighth Air Force heavy bomber offensive over Occupied Europe and Germany.

The USAAF 442d Troop Carrier Group flew C-47 Skytrain transports from the field between November 1944 and September 1945 when the airfield was returned to French control.

Several wooded areas to the southeast of the airfield are connected by now single-track concrete roads; within them are likely many wartime relics of destroyed buildings and other facilities common to Luftwaffe bases of the era.