It was originally built for the Jesuits, who arrived in Düsseldorf in 1619, and served as the "court church" for the Counts palatine of Neuburg (House of Palatinate-Neuburg) from 1708.

[3] The church is furnished with stucco by Johannes Kuhn from Strassburg[4] and life-size sculptures of the apostles and of saints of the Society of Jesus.

The mausoleum, designed by Venetian architect Simone del Sarto, contains the tombs of several Electors Palatine, including that of Johann Wilhelm.

Paintings by Ernst Deger can be found in the church's two side altars which are dedicated to the Virgin Mary.

The organ dates back to an instrument built in 1782 by Peter Kemper, in a casing by Bernhard Orlinski and Josef Zimmermann.