[3] In 1907, the Delta Alumni Association (St. Anthony Club of Philadelphia) decided it needed more room at the 1889 building at 22nd Street that it had been sharing with the undergraduate chapter of the fraternity.

[4] They acquired a property at 3637 Locust Walk and commissioned the Philadelphia architectural firm of Cope & Stewardson to design a new undergraduate chapter house.

[2][3][4] Cope and Stewardson had previously designed numerous structures on the University of Pennsylvania campus, and their plan for this building matches the others in style and materials.

[4] The fraternity house was described and pictured in George E. Nitzsche's 1918 book University of Pennsylvania: Its History, Traditions, Buildings and Memorials: Also a Brief Guide to Philadelphia.

[2] Cope and Stewardson incorporated the fraternity's symbolism into the building, including a stone tau cross above the second–story windows on the exterior.

[2] The dining room extends the full width of the building and features floor-to-ceiling wood paneling, a small fireplace, a large multi-light chandelier, and a circular plaster relief on the ceiling.

[2] The chapter house site originally included a free-standing literary building at its rear; however, this was demolished when the university acquired a portion of the property for expansion in the 1960s.