St. Catherine's traces its origins to the fall of 1864 when the Racine Dominican Sisters [2] established an all-girls' day and boarding academy.

In the fall of 1864, the Racine Dominican Sisters opened a day and boarding school for girls on property they purchased at Twelfth Street and Park Avenue.

Excavation for a new wing was begun in March 1947, and Archbishop Kiley of Milwaukee dedicated the building extending 175 feet south on Park Avenue in August 1949.

It was given to the school to use when the Dominican Sisters built their new motherhouse, Siena Center, and had the old convent building which stood on that property demolished.

He earned a state title in 2021,[12][13] and was named Racine All-County, Associated Press All-State,[14] and WBCA Coach of the Year.

[17] St. Catherine's High School is a member of the Wisconsin Interscholastic Athletic Association(WIAA) and the Metro Classic Conference.

[19] The first competitive game played was basketball, versus St. John's Cathedral of Milwaukee on Friday, January 8, 1926, in which St. Cat's lost 24 to 15.

[20] Beyer resigned in February 1927 and Eugene “Scrapiron” Young, a law student from the University of Notre Dame, was hired that March to fill the position.

That same year St. Cat's joined the Catholic Conference; which originally consisted of Pio Nono, St. Bonaventure, Messmer, Cathedral, and Marquette High Schools.

[24] At that time, private schools were barred from the WIAA, so the WCIAA was formed to sanction tournaments to determine their own state champions.

In 1972, the WISAA launched the girls' sports program, which officially sanctioned volleyball, basketball, tennis, and track state tournaments.