St. Elizabeth Hospital is a historic hospital complex located at Hannibal, Marion County, Missouri.

The original section was built in 1915, and is a three-story with raised basement, Second Renaissance Revival style rectangular red brick building.

It features a Palladian style window, large round arched openings on the 1+1⁄2-story brick portico, and limestone highlights.

[2]: 5 It was added to the National Register of Historic Places in 2012.

This article about a property in Marion County, Missouri on the National Register of Historic Places is a stub.